Latest News Updates from Cambridge Reactor Design

Latest Updates

Cambridge Reactor Design wins award to support Advanced Manufacturing...

Cambridge Reactor Design are leading the New reactor technology application and are working closely with partner organisations to exploit the capability of the technology with a focus on reducing complexity, streamlining the supply chain, improving product quality and its fit for purpose.

The REMEDIES project, launched in 2014, is headed up by GlaxoSmithKline with research led by the IfM’s Centre for International Manufacturing. It brings together key players in the end-to-end supply chain, including major contract manufacturing organisations, equipment manufacturers along with regulators, knowledge transfer networks and healthcare providers.

The project, due to be completed in March 2018, has several technology based application projects underpinned by two platform projects: clinical trials supply chains, led by GSK, and commercial supply chains led by IfM. This new announcement means that the project can move into the technology application phase.

Jag Srai, Head of CIM and REMEDIES Research Director, said: “Now the government funding has been approved, we can build on the considerable amount of progress made in the design of these production and supply chain transformative technologies, enabling investments in expertise and capital across the projects led by our industrial partners.

Interest from Infineum. March 2015

Infineum is a world-class formulator, manufacturer and marketer of petroleum. Cambridge Reactor Design is a world class technology provider in the area of continuous processing. We are very pleased to be working together...

The Polar Bear and the Fat Duck. January 2015

The Polar Bear continues to help dish up the treats in Melbourne, Australia... temporary location for the Fat Duck Restaurant. Our Polar Bear opens a new dimension in freezing sauces, purees, crèmes and foams. Moreover its supremely accurate, down to one hundredths of a degree - it needs to be to meet the quality requirements of the chefs at the Fat Duck!

See if you can guess where its used.

International Union of Crystallography 5th - 12th August 2014

It is tremendously satisfying for us to see tangible results coming from all our efforts over the past few years. With the line-up of fantastic new applications we are excited to show all of you in Montreal just how good our Polar Bear Plus is...

- just perfect for a cold martini and ummm cooling crystallization work.

BCA Spring Meeting 7th-10th April 2014,University of Loughborough. Crystallography - Looking to the future, learning from the past

Crystallography as a field of research has reached its centenary and 2014 has been designated by UNESCO as the International Year of Crystallography. The theme of the meeting is in tune with these milestones and will be “Crystallography @ 100: Looking to the future, learning from the past.”

It is appropriate therefore that we will be launching our newest range of Polar Bear Plus products - perfect for cooling crystallizations.

ARABLAB The Expo 2014 in Dubai from 17-20 March

Delighted to be exhibiting in ArabLab - our first time at the show.

We wll be showing our newest Zebrafish Automated Corrosion System with Intertek.


Developing a fully implantable, miniaturised ventricular assist device (VAD) for end-stage heart failure patients with facility for trans-cutaneous energy transfer (TET).

Limited availability of donor hearts has restricted the number of successful heart transplants in the UK and worldwide. Many patients receive a ventricular assist device (VAD or blood pump) as a substitute to a weak heart while awaiting heart transplantation. Currently VADs connect the heart (ventricular apex) to a centrifugal pump which in turn connects to the aorta via a vascular tube graft. Aorta conducts blood to all other organs and parts of the human body. Here, the pump is exterior to the heart (lying within the chest cavity) and is connected to the ventricular chamber by a short (1-2 inches long) metal tube through a hole (approximately 15-20 mm diameter) created in the ventricular apex. Electrical leads run from the pump through the abdominal wall and skin to batteries worn around the waist, which are in turn charged via an external power supply. Electrical leads passing through skin increase the risk of infection and limits quality of life of patients. They are prevented from having a shower or bath, which could not only predispose to infection but also potentially damage the electrical leads. In these VADs, blood comes in contact with significant amount of foreign material which predisposes to clot formation (thrombosis). In order to reduce this risk, patients are on long-term anti-coagulation (warfarin with or without aspirin), which in turn increases the risk of bleeding. We intend to construct a VAD with a miniaturised pump that can be implanted in the aortic valve or pulmonary valve position (for left and right ventricular support respectively). This avoids the need for extra-cardiac pumps or vascular grafts. The pump will be powered via leads that leave the pump to join a battery that can be implanted under the skin in the chest wall and charged trans-cutaneously from a domestic energy source.


2nd RSC/SCI Symposium on Continuous Processing and Flow Chemistry, September 24-25, 2013 Novartis, Horsham, UK .

We are very pleased to be exhibiting at the 2nd RSC/SCI Symposium on Continuous Processing and Flow Chemistry, September 24-25, 2013 Novartis, Horsham, UK

We’ll be delighted to offer you a cold drink.


Come and see the Polar Bear Plus family at Lab Innovations 2012.

CRD will be exhibiting the entire family at the NEC, Birmingham on November 7th-8th.

We’d love you to join us where we’ll be delighted to offer you a (very!) cold drink – just click the link to register for free.

Lab Innovations


Cambridge Reactor Design collaborating with Heston Blumenthal’s Team

Cambridge Reactor Design (CRD) are delighted to be working with the chefs at Heston Blumenthal’s experimental kitchen.

The chefs are evaluating CRD’s Polar Bear Advanced Cooling Technology at their kitchen in Bray. The Polar Bear accurately delivers any temperature from +5 to -90C at the touch of a button. Custom made moulds ensure good thermal transfer to the food being prepared.

Initial results have been exciting and the chefs are impressed with the accurate temperature control that can be achieved and the speed of heat transfer. Following good success with current recipes, the plan is to extend the evaluation by exploring the potential to design new menu items that could only be prepared using this enabling technology.


Polar BearPlus

CRD are pleased to announce that in response to customer feedback the Polar Bear Plus is now available in a choice of three models to meet all your laboratory needs. Whichever model you choose, you’ll be able to achieve system temperatures from –40 to +150C at the touch of a button – no ice, solvents or heat transfer fluids are required – all within a low energy, space-saving unit.

Polar Bear Plus

is a stirrer hot&cold plate suited to many applications. Simply turn it on and set the temperature of the plate or the contents. Insulated formers are available in a range of sizes to ensure good thermal transfer

Polar Bear Plus - Crystal

, developed with input from the chemists at SAFC Pharmorphix®, includes more sophisticated temperature control. The temperature gradients that can be achieved, together with temperature profiling/cycling, makes this the perfect choice for your crystallisation investigations. Choose from the interchangeable 2ml, 5ml or 20ml multiple vial holders, or opt for a 100ml or 250ml flask holder.

Polar Bear Plus - Flow Synthesiser

, was designed in collaboration with the chemists at the state of the art Innovative Technology Centre (ITC) at the University of Cambridge to give them more flexibility and control over the temperatures for their continuous chemistry reactions – the performance and the compact design is allowing them to link units together to carry out multi step reactions at different temperatures.

For further information please visit the dedicated Polar Bear Plus page


CRD and Uniqsis launch the Polar Bear for flow chemistry

The Polar Bear Tubular Reactor for continuous chemistry applications has been launched by CRD and Uniqsis. With a temperature range of ambient to –88C achieved at the touch of a button, the Polar Bear represents a significant advance in the flow chemistry field. The unit is available both in a standalone format, or integrated with Uniqsis’ FlowSyn to make up the FlowSyn Polar Bear system. To find out more please read the full press release and see our Polar Bear leaflet.


The Gastropod Gas Liquid Module is now available.

CRD are pleased to announce that the Gastropod Gas Introduction Module for continuous chemistry applications is now available. Based on an original concept from the chemists at Cambridge University, the Gastropod uses semi-permeable membrane technology to improve contact between the gas and liquid phases. The module has been successfully demonstrated with a number of reactive gases, including hydrogen, carbon monoxide, carbon dioxide, oxygen and ozone, as well as with a wide range of solvents such as methanol, THF, dichloromethane and acetonitrile. Publications from the Ley group are in press and examples will be posted on our case studies page in due course.

CRD exhibit Polar Bear at 28th SCI Process Development Symposium

Cambridge Reactor Design will be exhibiting their new Polar Bear Advanced Cooling Technology in Cambridge UK at the 28th SCI Process Development Symposium, 8-10 December 2010. If you’d like to achieve efficient cooling at the touch of a button, come and talk to us about your application.

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